"Database of Curated Mutations (DoCM)"[submitter] AND "ERBB2"[gene] - ClinVar

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Items: 23

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 376205	NM_004448.4(ERBB2):c.926G>C (p.Gly309Ala)	ERBB2 (G279A +7 more)	Single nucleotide variant (missense variant +1 more)	Breast neoplasm	GLikely pathogenic
Select item 376138	NM_004448.4(ERBB2):c.926G>A (p.Gly309Glu)	ERBB2 (G279E +7 more)	Single nucleotide variant (missense variant +1 more)	Malignant tumor of urinary bladder +1 more	GPathogenic/Likely pathogenic
Select item 376189	NM_004448.4(ERBB2):c.929C>T (p.Ser310Phe)	ERBB2 (S280F +7 more)	Single nucleotide variant (missense variant +1 more)	Gastric adenocarcinoma +9 more	GLikely pathogenic
Select item 376188	NM_004448.4(ERBB2):c.929C>A (p.Ser310Tyr)	ERBB2 (S280Y +7 more)	Single nucleotide variant (missense variant +1 more)	not provided	GPathogenic
Select item 376344	NM_004448.4(ERBB2):c.2033G>A (p.Arg678Gln)	ERBB2 (R648Q +13 more)	Single nucleotide variant (missense variant +2 more)	Prostate adenocarcinoma +4 more	GLikely pathogenic
Select item 376404	NM_004448.4(ERBB2):c.2263T>A (p.Leu755Met)	ERBB2 (L725M +17 more)	Single nucleotide variant (missense variant +2 more)	Papillary renal cell carcinoma, sporadic +6 more	GLikely pathogenic
Select item 375990	NM_004448.4(ERBB2):c.2264_2278del (p.Leu755_Thr759del)	ERBB2	Deletion (inframe_deletion +2 more)	Breast neoplasm	GPathogenic
Select item 13877	NM_004448.4(ERBB2):c.2263_2264delinsCC (p.Leu755Pro)	ERBB2 (L755P +17 more)	Indel (missense variant +2 more)	Breast neoplasm +7 more	GPathogenic/Likely pathogenic
Select item 376343	NM_004448.4(ERBB2):c.2264T>G (p.Leu755Trp)	ERBB2 (L725W +17 more)	Single nucleotide variant (missense variant +2 more)	Malignant neoplasm of body of uterus +6 more	GLikely pathogenic
Select item 376035	NM_004448.4(ERBB2):c.2264T>C (p.Leu755Ser)	ERBB2 (L725S +17 more)	Single nucleotide variant (missense variant +2 more)	Malignant neoplasm of body of uterus +6 more	GLikely pathogenic
Select item 376403	NM_004448.4(ERBB2):c.2305G>A (p.Asp769Asn)	ERBB2 (D739N +17 more)	Single nucleotide variant (missense variant +2 more)	Neoplasm of uterine cervix +4 more	GLikely pathogenic
Select item 375992	NM_004448.4(ERBB2):c.2305G>T (p.Asp769Tyr)	ERBB2 (D739Y +17 more)	Single nucleotide variant (missense variant +2 more)	Neoplasm of uterine cervix +4 more	GPathogenic/Likely pathogenic
Select item 375991	NM_004448.4(ERBB2):c.2305G>C (p.Asp769His)	ERBB2 (D739H +17 more)	Single nucleotide variant (missense variant +2 more)	Neoplasm of uterine cervix +4 more	GPathogenic/Likely pathogenic
Select item 44988	NM_004448.4(ERBB2):c.2326_2327insTGT (p.Gly776delinsValCys)	ERBB2	Insertion (inframe_indel +2 more)	Non-small cell lung carcinoma	GLikely pathogenic
Select item 13879	NM_004448.4(ERBB2):c.2326G>A (p.Gly776Ser)	ERBB2 (G776S +18 more)	Single nucleotide variant (missense variant +2 more)	Gastric adenocarcinoma +2 more	GPathogenic/Likely pathogenic
Select item 376406	NM_004448.4(ERBB2):c.2329G>A (p.Val777Met)	ERBB2 (V747M +18 more)	Single nucleotide variant (missense variant +2 more)	Gastric adenocarcinoma +2 more	GLikely pathogenic
Select item 376036	NM_004448.4(ERBB2):c.2329G>C (p.Val777Leu)	ERBB2 (V747L +18 more)	Single nucleotide variant (missense variant +2 more)	Breast neoplasm	GLikely pathogenic
Select item 44991	NM_004448.4(ERBB2):c.2329G>T (p.Val777Leu)	ERBB2 (V777L +18 more)	Single nucleotide variant (missense variant +2 more)	not specified	GUncertain significance
Select item 375993	NM_004448.4(ERBB2):c.2333_2334insGCTCCCCAG (p.Gly778_Ser779insLeuProSer)	ERBB2	Insertion (inframe_insertion +2 more)	Breast neoplasm	GPathogenic
Select item 376333	NM_004448.4(ERBB2):c.2354T>C (p.Leu785Pro)	ERBB2 (L755P +18 more)	Single nucleotide variant (missense variant +2 more)	Breast neoplasm	GLikely pathogenic
Select item 375994	NM_004448.4(ERBB2):c.2524G>A (p.Val842Ile)	ERBB2 (V812I +19 more)	Single nucleotide variant (missense variant +2 more)	not provided	GUncertain significance
Select item 13880	NM_004448.4(ERBB2):c.2570A>G (p.Asn857Ser)	ERBB2 (N857S +19 more)	Single nucleotide variant (missense variant +2 more)	Ovarian adenocarcinoma +1 more	GPathogenic/Likely pathogenic
Select item 375995	NM_004448.4(ERBB2):c.2686C>T (p.Arg896Cys)	ERBB2 (R866C +21 more)	Single nucleotide variant (missense variant +2 more)	Breast neoplasm	GPathogenic

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Items: 23